List of 55 Grants to nPOD Investigators from the Helmsley Charitable Trust George S. Eisenbarth nPOD Award for Team Science

(2015-2021, as of October 13, 2021, from Grant awards 2018-PG-T1D-060 and 2015-PG-T1D-052)

Awards made in support of pilot studies:

Butler, Alexandra. UCLA, Los Angeles, CA, USA.
Growth and Development of the Endocrine Pancreas in Humans: Extrapolating Normal Physiology to the Regenerative Capacity of the Endocrine Compartment in Type 1 and Type 2 Diabetes.
$27,500 from Helmsley Charitable Trust Award 2015-PG-T1D-052.

Campbell-Thompson, Martha. University of Florida.
Beta cell regeneration for type 1 diabetes.
$27,500 from Helmsley Charitable Trust Award 2015-PG-T1D-052.

Creusot, Remi. Columbia University Medical Center, Columbia Center for Translational Immunology, New York, NY, USA.
Exacerbated expression of cytotoxic genes in the PLNs of T1D patients.
$29,645 from Helmsley Charitable Trust Award 2015-PG-T1D-052.

Dor, Yuval. Hebrew University, Jerusalem, Israel.
Beta cell DNA double strand breaks in Type 1 diabetes.
$27,500 from Helmsley Charitable Trust Award 2015-PG-T1D-052.

Feng, Ji-Ming. Louisiana State University.
The cellular distribution of Golli protein in human pancreatic islets.
$11,000 from Helmsley Charitable Trust Award 2018-PG-T1D-060.

Forbes, Josephine. Mater Research Institute – The University of Queensland, Australia.
Advanced glycation and pancreatic islet function.
$16,000 from Helmsley Charitable Trust Award 2015-PG-T1D-052.

Friedman, Rachel. National Jewish Health; University of Colorado Denver, Colorado, USA.
Mononuclear phagocyte populations in T1D islets.
$27,500 from Helmsley Charitable Trust Award 2015-PG-T1D-052.

Itzkovitz, Shalev. Weizmann Institute of Science
Transcriptional heterogeneity in the Intact Human Pancreas.
$27,500 from Helmsley Charitable Trust Award 2018-PG-T1D-060.

Levine, Fred. Sanford Burnham Prebys Medical Discovery Institute.
Assessment of Islet Cell Transdifferentiation in Type 1 Diabetes.
$27,500 from Helmsley Charitable Trust Award 2015-PG-T1D-052.

Marjomäki, Varpu. University of Jyväskylä, Finland.
Detection of Enterovirus infection and replication in nPOD tissue pancreas samples using immuno electron microscopy (immuno-EM).
$51,422 from Helmsley Charitable Trust Award 2018-PG-T1D-060.

Morris, Margaret. Eastern Virginia Medical School, Norfolk, VA, USA.
Dissecting the role intestinal NK cells play in T1D pathogenesis.
$23,396 from Helmsley Charitable Trust Award 2015-PG-T1D-052.

Rodriguez-Calvo, Teresa. Helmholtz Zentrum München, Helmholtz Diabetes Center, Germany.
Proinsulin processing and presentation in human type 1 diabetes: a beta cell – T cell perspective.
$55,000 from Helmsley Charitable Trust Award 2018-PG-T1D-060.

Sander, Maike. University of California, San Diego.
Single cell analysis of the human pancreas in type 1 diabetes.
$27,500 from Helmsley Charitable Trust Award 2018-PG-T1D-060.

Sarvetnick, Nora. University of Nebraska Medical Center.
Pancreatic antibacterial responses in T1D.
$27,309 from Helmsley Charitable Trust Award 2015-PG-T1D-052.

Thomas, Jainy & Perron, Herve. University of Utah.
Identification of HERV-W copies and insertion sites associated with T1D in human genomes.
$55,000 from Helmsley Charitable Trust Award 2018-PG-T1D-060.

Wallet, Mark. University of Florida.
Role of CCL21 in directing immune invasion of pancreatic islets.
$10,585 from Helmsley Charitable Trust Award 2018-PG-T1D-060.

Wang, Julia. Florida State University.
Harnessing the power of beta cell regeneration to treat diabetes.
$44,044 from Helmsley Charitable Trust Award 2018-PG-T1D-060.

Zorn, Emmanuel. Columbia University.
Immunoregulation of Type 1 Diabetes.
$27,500 from Helmsley Charitable Trust Award 2015-PG-T1D-052.

Awards made in support of studies of pancreas slices/nPOD Pancreas Slice Group:

Benninger, Richard. University of Colorado Anschutz Medical Campus.
Huising, Mark. University of California Davis.
Characterizing endocrine cell cross talk in human islets in situ during T1D.
$35,361 from Helmsley Charitable Trust Award 2018-PG-T1D-060.

Bogdani, Marika. Benaroya Research Institute, Seattle.
Study of the contributions of islet extracellular matrix to islet immune cell infiltration and beta cell dysfunction using pancreas slices from non-diabetic and T1D donors.
$30,636 from Helmsley Charitable Trust Award 2018-PG-T1D-060.

Caicedo, Alejandro. University of Miami School of Medicine, Department of Medicine, Division of Endocrinology, Diabetes and Metabolism.
nPOD Pancreas Slice Group.
$66,000 from Helmsley Charitable Trust Award 2015-PG-T1D-052.

Gaisano, Herbert. University of Toronto, Canada.
Characterization and rescue of intrinsic and paracrine defects of human T1D alpha-cells.
$ 54,758 from Helmsley Charitable Trust Award 2018-PG-T1D-060.

Gerling, Ivan. University of Tennessee Health Science Center.
Study of the contributions of islet extracellular matrix to islet immune cell infiltration and beta cell dysfunction using pancreas slices from non-diabetic and T1D donors.
$52,766 from Helmsley Charitable Trust Award 2018-PG-T1D-060.

Itkin-Ansari, Pamela. Sanford-Burnham-Prebys Medical Discovery Institute.
The role inflammatory signaling crosstalk on human exocrine and beta cells.
$44,440 from Helmsley Charitable Trust Award 2018-PG-T1D-060.

Kent, Sally. University of Massachusetts Medical School, Worcester, MA.
Islet and Peri-Islet Factors Defining Lymphocytic Infiltrate and Islet β-Cell HLA Class II Expression Heterogeneity.
$50,000 from Helmsley Charitable Trust Award 2018-PG-T1D-060.

Korpos, Eva and Sorokin, Lydia. Institute of Physiological Chemistry and Pathobiochemistry and Cells-in-Motion (CiM) Cluster of Excellence, University of Münster, Münster, Germany.
Study of the contributions of islet extracellular matrix to islet immune cell infiltration and beta cell dysfunction using pancreas slices from non-diabetic and T1D donors.
$20,291 from Helmsley Charitable Trust Award 2018-PG-T1D-060.

Kusmartseva, Irina; Campbell-Thompson, Martha; Brusko, Todd. University of Florida, College of Medicine, Diabetes Institute.
nPOD Pancreas Slice Group.
$76,728 from Helmsley Charitable Trust Award 2015-PG-T1D-052.

Nakayama, Maki. University of Colorado Denver Anschutz Medical Campus.
Immune cell repertoires in (pro)insulin positive and negative pancreatic islets.
$55,000 from Helmsley Charitable Trust Award 2018-PG-T1D-060.

Pugliese, Alberto. University of Miami School of Medicine, Department of Medicine, Diabetes Research Institute.
nPOD Pancreas Slice Group.
$33,000 from Helmsley Charitable Trust Award 2015-PG-T1D-052.

Rodriguez-Calvo, Teresa. Helmholtz Zentrum München, Helmholtz Diabetes Center, Germany.
Defining the link between Islet prohormone accumulation and secretion in type 1 diabetes.
$20,156 from Helmsley Charitable Trust Award 2018-PG-T1D-060.

Sims, Emily. Indiana University School of Medicine.
Defining the link between Islet prohormone accumulation and secretion in type 1 diabetes.
$33,000 from Helmsley Charitable Trust Award 2018-PG-T1D-060.

Speier, Stephan. Paul Langerhans Institute Dresden, Helmholtz Zentrum München, Germany.
nPOD Pancreas Slice Group.
$45,045 from Helmsley Charitable Trust Award 2015-PG-T1D-052.

Awards made in support of studies of the Extracellular Matrix Group:

Bogdani, Marika & Wight, Thomas. Matrix Biology Program, Benaroya Research Institute, Seattle, WA, USA.
$71,500 from Helmsley Charitable Trust Award 2015-PG-T1D-052.

Bogdani, Marika. Matrix Biology Program, Benaroya Research Institute, Seattle, USA.
Morphologic and Molecular Characterization of Human Islet Microvasculature during Islet Autoimmunity and Type 1 Diabetes.
$49,104 from Helmsley Charitable Trust Award 2015-PG-T1D-052.

Gerling, Ivan. Department of Internal Medicine, Center for Integrative and Translational Genomics, University of Tennessee Health Science Center.
Morphologic and Molecular Characterization of Human Islet Microvasculature during Islet Autoimmunity and Type 1 Diabetes.
$60,678 from Helmsley Charitable Trust Award 2015-PG-T1D-052.

Giepmans, Ben. Department of Cell Biology, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, the Netherlands.
Morphologic and Molecular Characterization of Human Islet Microvasculature during Islet Autoimmunity and Type 1 Diabetes.
$3,388 from Helmsley Charitable Trust Award 2015-PG-T1D-052.

Korpos, Eva and Sorokin, Lydia. Institute of Physiological Chemistry and Pathobiochemistry and Cells-in-Motion (CiM) Cluster of Excellence, University of Münster, Münster, Germany.
$71,500 from Helmsley Charitable Trust Award 2015-PG-T1D-052. 

Korpos, Eva & Sorokin, Lydia. Institute of Physiological Chemistry and Pathobiochemistry and Cells-in-Motion (CiM) Cluster of Excellence, University of Münster, Münster, Germany.
Morphologic and Molecular Characterization of Human Islet Microvasculature during Islet Autoimmunity and Type 1 Diabetes.
$25,960 from Helmsley Charitable Trust Award 2015-PG-T1D-052.

Simeonovic, Charmaine & Parish, Christopher. Diabetes/Transplantation Immunobiology Laboratory, Department of Immunology and Infectious Disease, and Cancer and Vascular Biology Group, Department of Cancer Biology and Therapeutics, The John Curtin School of Medical Research, The Australian National University, Canberra, ACT, 2601 Australia
$56,702 from Helmsley Charitable Trust Award 2015-PG-T1D-052.

Awards made in support of the nPOD Autoimmunity Group:

Brusko, Todd. University of Florida, College of Medicine, Diabetes Institute,
Robins, Harlan. Adaptive Biotechnologies, Inc.
$252,417 from Helmsley Charitable Trust Award 2015-PG-T1D-052.

Cambier, John. University of Colorado School of Medicine, Anschutz Medical Campus, Department of Immunology and Microbiology.
$124,336 from Helmsley Charitable Trust Award 2015-PG-T1D-052.

Campbell-Thompson, Martha. University of Florida, College of Medicine, Diabetes Institute.
$33,000 from Helmsley Charitable Trust Award 2015-PG-T1D-052.

Creusot, Remi. Columbia University Medical Center, Columbia Center for Translational Immunology, New York, NY, USA.
$16,000 from Helmsley Charitable Trust Award 2015-PG-T1D-052.

Davidson, Howard. University of Colorado, School of Medicine, Anschutz Medical Campus, Barbara Davis Center for Diabetes (BDC), Denver, Colorado, USA.
$33,000 from Helmsley Charitable Trust Award 2015-PG-T1D-052.

Fife, Brian. University of Minnesota, Medical School, Department of Medicine/
$33,000 from Helmsley Charitable Trust Award 2015-PG-T1D-052.

Fousteri, Georgia. San Raffaele Scientific Institute, Milano, Italy.
$33,000 from Helmsley Charitable Trust Award 2015-PG-T1D-052.

Hamad Abdel. Johns Hopkins University School of Medicine, Baltimore, MD, USA.
$22,000 from Helmsley Charitable Trust Award 2015-PG-T1D-052.

Haskins, Kathrin. University of Colorado School of Medicine, Anschutz Medical Campus, Department of Immunology and Microbiology.
$33,000 from Helmsley Charitable Trust Award 2015-PG-T1D-052.

Homann, Dirk. Icahn School of Medicine at Mount Sinai, New York, NY, USA.
$27,500 from Helmsley Charitable Trust Award 2015-PG-T1D-052.

Kent, Sally. University of Massachusetts Medical School, Department of Medicine, Worcester, MA, USA.
$14,049 from Helmsley Charitable Trust Award 2015-PG-T1D-052.

Mallone, Roberto. INSERM U1016 – Cochin Institute, Paris, France.
In situ analysis of ZnT8-reactive CD8+ T cells in pancreatic lymph nodes and islets.
$26,950 from Helmsley Charitable Trust Award 2015-PG-T1D-052.

Michels, Aaron. University of Colorado, School of Medicine, Anschutz Medical Campus, Barbara Davis Center for Diabetes (BDC), Denver, Colorado, USA.
$55,000 from Helmsley Charitable Trust Award 2015-PG-T1D-052.

Nakayama, Maki. University of Colorado, School of Medicine, Anschutz Medical Campus, Barbara Davis Center for Diabetes (BDC).
$97,317 from Helmsley Charitable Trust Award 2015-PG-T1D-052. 

Reijonen, Helena.  Department of Diabetes Immunology, Beckman Research Institute of the City of Hope, Duarte, CA, USA.
$35,003 from Helmsley Charitable Trust Award 2015-PG-T1D-052.

Von Herrath, Matthias. La Jolla Institute for Allergy and Immunology, San Diego, CA, USA.
$33,000 from Helmsley Charitable Trust Award 2015-PG-T1D-052.