2017 Publications (33)

Kusmartseva I, Beery M, Philips T, Selman S, Jadhav P, Wasserfall C, Muller A,Pugliese A, Longmate JA, Schatz DA, Atkinson MA, Kaddis JS. (2017) Hospital time prior to death and pancreas histopathology: implications for future studies. Diabetologia. 2017 Nov 11. doi: 10.1007/s00125-017-4494-x.

Semeraro ML, Glenn LM, Morris MA. (2017) The Four-Way Stop Sign: Viruses, 12-Lipoxygenase, Islets, and Natural Killer Cells in Type 1 Diabetes Progression. Front Endocrinol (Lausanne). 2017 Sep 25;8:246. doi: 10.3389/fendo.2017.00246.

Syed F. Hassnain Waqas, Anh Cuong Hoang, Ya-Tin Lin, Grace Ampem, Hind Azegrouz, Lajos Balogh, Julianna Thuróczy, Jin-Chung Chen, Ivan C. Gerling, Sorim Nam, Jong-Seok Lim, Juncal Martinez-Ibañez, José T. Real, Stephan Paschke, Raphaëlle Quillet, Safia Ayachi, Frédéric Simonin, E. Marion Schneider,11 Jacqueline A. Brinkman, Dudley W. Lamming, Christine M. Seroogy, and Tamás Röszer. (2017) Neuropeptide FF increases M2 activation and self-renewal of adipose tissue macrophages. J Clin Invest. 2017;127(7):2842-2854. doi:10.1172/JCI90152

Jacobsen LM, Posgai A, Seay HR, Haller MJ, Brusko TM. (2017) T Cell Receptor Profiling in Type 1 Diabetes. Curr Diab Rep. 2017 Oct 11;17(11):118. doi: 10.1007/s11892-017-0946-4.

Levet S, Medina J, Joanou J, Demolder A, Queruel N, Réant K, Normand M, Seffals M, Dimier J, Germi R, Piofczyk T, Portoukalian J, Touraine JL, Perron H. (2017) An ancestral retroviral protein identified as a therapeutic target in type-1 diabetes. JCI Insight. 2017 Sep 7;2(17). pii: 94387. doi: 10.1172/jci.insight.94387.

Kent SC, Mannering SI, Michels AW, Babon JAB. (2017). Deciphering the Pathogenesis of Human Type 1 Diabetes (T1D) by Interrogating T Cells from the “Scene of the Crime”. Current Diabetes Reports. 2017 Sep 2; 17(10):95. doi: 10.1007/s11892-0170-0915-y.

Nyalwidhe JO, Grzesik WJ, Burch TC, Semeraro ML, Waseem T, Gerling IC, Mirmira RD, Morris MA, Nadler JL. (2017) Comparative Quantitative Proteomic Analysis of Disease Stratfied Laser Captured Microdissected Human Islets Identifies Proteins and Pathways Potentially Related to Type 1 Diabetes. PLoS One. 2017 SEp 6; 12(9):e0183908. doi: 10.1371/journal.pone. 0183908. eCollection 2017.

Wasserfall C, Nick HS, Campbell-Thompson M, Beachy D, Haataja L, Kusmartseva I, Posgai A, Beery M, Rhodes C, Bonifacio E, Arvan P, Atkinson M. (2007) Persistence of Pancreatic Insulin mRNA Expression and Proinsulin Protein in Type 1 Diabetes Pancreata. Cell Metab. 2017 Sep 5;26(3):568-575.e3. doi: 10.1016/j.cmet.2017.08.013.

Pugliese, A. (2017). Autoreactive T Cells in Type 1 Diabetes. J Clin Invest. 2017 Aug 1;127(8):2881-2891. doi: 10.1172/JCI94549. Epub 2017 Aug 1.

Sebastiani G, Ventriglia G, Stabilini A, Socci C, Morsiani C, Laurenzi A, Nigi L, Formichi C, Mfarrej B, Petrelli A, Fousteri G, Brusko TM, Dotta F, Battaglia M. (2017) Regulatory T-cells from pancreatic lymphnodes of patients with type-1 diabetes express increased levels of microRNA miR-125a-5p that limits CCR2 expression. Sci Rep. 2017 Jul 31;7(1):6897. doi: 10.1038/s41598-017-07172-1.

Rodnoi P, Rajkumar M, Moin ASM, Georgia SK, Butler, AE, Dhawan S. (2017). Neuropeptide Y Expression Marks Partially Differentiated β Cells in Mice and Humans. JCI Insight. 2017 Jun 15; 2(12). pii: 94005. doi:  10.1172/jci.insight.94005.

Thivolet C, Vial G, Cassel R, Rieusset J, Madec AM. (2017) Reduction of Endoplasmic Reticulum-Mitochondria Interactions in Beta Cells from Patients with Type 2 Diabetes. PLoS One. 2017 Jul 25;12(7):e0182027. doi: 10.1371/journal.pone.0182027.

Schludi B, Moin ASM, Montemurro C, Gurlo T, Matveyenko AV, Kirakossian D, Dawson DW, Dry SM, Butler PC, Butler AE. (2017) Islet Inflammation and Ductal Proliferation may be Linked to Increased Pancreatitis Risk in Type 2 Diabetes. JCI Insight. 2017 Jul 6;2(13). pii: 92282. doi: 10.1172/jci.insight.92282.

Moin AS, Butler PC, Butler AE. (2017) Increased Proliferation of the Pancreatic Duct Gland Compartment in Type 1 Diabetes. J Clin Endocrinol Metab. 2017 Jan 1;102(1):200-209. doi: 10.1210/jc.2016-3001.

Genoni A, Canducci F, Rossi A, Broccolo F, Chumakov K, Bono G, Salerno-Uriarte J, Salvatoni A, Pugliese A, Toniolo A. (2017) Revealing enterovirus infection in chronic human disorders: An integrated diagnostic approach. Sci Rep. 2017 Jul 10;7(1):5013. doi: 10.1038/s41598-017-04993-y.

Rodriguez-Calvo T, Atkinson M, von Herrath M. (2017) β-Cell mass versus function in type 1 diabetes mellitus: truth or dare? Nat Rev Endocrinol. 2017 Jul 7. doi: 10.1038/nrendo.2017.83.

Jacobsen LM, Haller MJ, Parish A, Gurka MJ, Levine SR, Wasserfall C, Campbell-Thompson M, Kaddis J, Pugliese A, Atkinson MA, Schatz DA. (2017) High Illicit Drug Abuse and Suicide in Organ Donors with Type 1 Diabetes. Diabetes Care. 2017 Jul 5. pii: dc170996. doi: 10.2337/dc17-0996.

Wagas SFH, Hoang AC, Lin YT, Ampem G, Azegrouz H, Balogh L, Thuróczy J, Chen JC, Gerling IC, Nam S, Lim JS, Martinez-Ibañez J, Real JT, Paschke S, Quillet R, Ayachi S, Simonin F, Schneider EM, Brinkman JA, Lamming DW, Seroogy CM, Röszer T. (2017) Neuropeptide FF Increases M2 Activation and Self-Renewal of Adipose Tissue Macrophages. Journal of Clinical Investigation. 2017 Jun 5. pii: 90152. doi: 10.1172/JCI90152.

Bloem SJ, Roep BO (2017). The Elusive Role of B Lymphocytes and Islet Autoantibodies in (Human) Type 1 Diabetes. Diabetologia. 2017 Jul;60(7):1185-1189. doi: 10.1007/s00125-017-4284-5. Epub 2017 Apr 24.

Phelps E, Cianciaruso C, Santo-Domingo J, Pasquier M, Galliverti G, Piemonti L, Berishvili E, Burri O, Wiederkehr A, Hubbell J, Baekkeskov S (2017). Advances in Pancreatic Islet Monolayer Culture on Glass Surfaces Enable Super-Resolution Microscopy and Insights into Beta Cell Ciliogenesis and Prolifertation. Scientific Reports. 2017 Apr 12; 7:45961. doi: 10.1038/srep45961.

Aguayo-Mazzucato C, van Haaren M, Mruk M, Lee T, Crawford C, Hollister-Lock J, Sullivan B, Johnson J, Ebrahimi A, Dreyfuss J, Van Deursen J, Weir G, Bonner-Weir S (2017). β Cell Aging Markers Have Heterogeneous Distribution and Are Induced by Insulin Resistance. Cell Metabolism. 2017 Apr 4;25(4):898-910.e5. doi: 10.1016/j.cmet.2017.03.015.

Van der Meulen T, Mawla A, DiGruccio M, Adams M, Nies V, Dólleman S, Liu S, Ackermann A, Cácerres E, Hunter A, Kaestner K, Donaldson C, Huising M (2017). Virgin Beta Cells Persist throughout Life at a Neogenic Niche within Pancreatic Islets. Cell Metabolism. 2017 Apr 4; 25(4):911-926.e6. doi:10.1016/j.cmet.2017.03.017.

Kent S, Babon J (2017). Narrowing in on the Anti-β Cell-specific T Cells: Looking ‘Where the Action Is’. Curr Opin Endocrinol Diabetes Obes. 2017 Apr; 24(2):98-102. doi: 10.1097/MED.

Moin A, Cory M, Ong A, Choi J, Dhawan S, Butler P, Butler A (2017). Pancreatic Nonhormone Expressing Endocrine Cells in Children with Type 1 Diabetes. Journal of the Endocrine Society. 2017 Mar 24. 1(5):385-395.

Anquetil F, Sabouri S, Thivolet C, Rodriguez-Calvo T, Zapardiel-Gonzalo J, Amirian N, Schneider D, Castillo E, Lajevardi Y, von Herrath M (2017). Alpha Cells, the Main Source of IL-1β in Human Pancreas. Journal of Autoimmunity. 2017 Mar 18. pii: S0896-8411(16)30268-2. doi: 10.1016/j.jaut.2017.03.006.

Lam C, Jacobson D, Rankin M, Cox A, Kushner J (2017). β-Cells Persist in T1D Pancreata without Evidence for Ongoing β-Cell Turnover or Neogenesis. Journal of Clinical Endocrinology & Metabolism. 2017 Feb 27. doi: 10.1210/jc.2016-3806.

Willcox A, Richardson S, Walker L, Kent S, Morgan N, Gillespie K (2017). Germinal Centre Frequency is Decreased in Pancreatic Lymph Nodes from Individuals with Recent Onset Type 1 Diabetes. Diabetologia. 2017 Feb 17. doi: 10.1007/s00125-017-4221-7.

Kolb H, von Herrath M (2017). Immunotherapy for Type 1 Diabetes: Why do Current Protocols Not Halt the Underlying Disease Process? Cell Metabolism. 2017 Feb 7; 25(2):233-241. doi: 10.1016/j.c.met.2016.10.009.

Martin C, Krogvold L, Farik S. Amirapu S, Wu F, Reddy S, Dahl-Jørgensen K (2017). An Immunohistochemical Study of Nitrotyrosine Expression in Pancreatic Islets of Cases with Increasing Duration of Type 1 Diabetes and without Diabetes. Histochem Cell Biology. 2017 Feb 2. doi: 10.1007/s00418-016-1533-5.

Philips T, Kusmartseva I, Gerling I, Campbell-Thompson M, Wasserfall C, Pugliese A, Longmate J, Schatz D, Atkinson M, Kaddis J (2017). Factors That Influence the Quality of RNA from the Pancreas of Organ Donors. Pancreas. 2017 Feb ;46(2):252-259. doi: 10.1097/MPA.0000000000000717.

Rodriguez-Calvo R, Zapardiel-Gonzalo J, Amirian N, Castillo E, Lajevardi Y, Krogvold L, Dahl-Jørgensen K, von Herrath M (2017). Increase in Pancreatic Proinsulin and Preservation of Beta Cell Mass in Autoantibody Positive Donors prior to Type 1 Diabetes Onset. Diabetes. 2017 Jan 30. doi: 10.2337/db16-1343.

Kirk R, Pyke C, von Herrath M, Hasselby J, Pedersen L, Mortensen P, Bjerre Knudsen L, Coppieters K (2017). Immunohistochemical Assessment of Glucagon-Like Peptide 1 Receptor (GLP-1R) Expression in the Pancreas of Patients with Type 2 Diabetes. Diabetes Obesity Metabolism. 2017 Jan 17. doi: 10.1111/dom.12879. [Epub ahead of print].

Campbell-Thompson M, Atkinson M, Butler A, Giepmans B, von Herrath M, Hyöty H, Kay T, Morgan N, Powers A, Pugliese A, Richardson S, In’t Veld P (2017). Re-Addressing the 2013 Consensus Guidelines for the Diagnosis of Insulitis in Human Type 1 Diabetes: Is Change Necessary? Diabetologia. 2017 Jan 9. doi: 10.1007/s00125-016-4195-x. [Epub ahead of print].