Beta Cell Regeneration

Investigators in this group are using nPOD samples to try and determine if there is evidence for Beta cell regeneration in persons with type 1 diabetes.

Mark Atkinson	Douglas Melton
Amy Cox	Scott Noggle
Dieter Egli	Christopher Rhodes
Leonard Harrison*	Patrick Rowe
Mattias Hebrok	Srinath Sanda
Jake Kushner*	Andrew Stewart
Ruddy Leibel

 

Mark Atkinson, Ph.D.
University of Florida
Project: The ductal pancreatic progenitor microenvironment in type 1 diabetes
Principal Investigator: Patrick Rowe, Ph.D.

 

 

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Amy Cox, Ph.D.
University of Pittsburgh Medical Center
Project: Multidisciplinary approaches to driving human beta cell replication
Principal Investigator: Andrew Stewart, M.D.

 

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Dieter Egli, Ph.D.
Columbia University
Project: Generation of pluripotent stem cells from diabetics
Co-Investigators: Rudy Leibel, M.D. Scott Noggle, Ph.D.

 

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Leonard Harrison, D.Sc.*
Walter & Eliza Hall Institute of Medical Research
Project: Adult islet progenitor cell markers

 

 

 

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Matthias Hebrok, Ph.D.
University of California, San Francisco
Project: Investigating the de-differentiated state of the ß-cell in human diabetic patient tissues

 

 

 

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Jake Kushner, M.D.*
Baylor College of Medicine
Project: Do de-granulated ß-cells persist in type 1 diabetes?

 

 

 

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Rudy Leibel, M.D.
Columbia University
Project: Generation of pluripotent stem cells from diabetics
Principal Investigator: Dieter Egli, Ph.D.

 

 

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Douglas Melton, Ph.D.
Harvard University
Project: Generation of tools to distinguish human pancreatic cell populations

 

 

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Scott Noggle, Ph.D.
Columbia University
Project: Generation of pluripotent stem cells from diabetics
Principal Investigator: Dieter Egli, Ph.D.

 

 

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Christopher Rhodes, Ph.D.
University of Chicago
Project: "Empty Beta Cells" in type 1 diabetes

 

 

 

 

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Patrick Rowe, Ph.D.
University of Florida
Project: The ductal pancreatic progenitor microenvironment in type 1 diabetes
Co-Investigator: Mark Atkinson, Ph.D.

 

 

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Srinath Sanda, M.D.
Benaroya Research Institute
Project: Analysis of beta cell senescence in T1D subjects

 

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Andrew Stewart, M.D.
University of Pittsburgh Medical Center
Project: Multidisciplinary approaches to driving human beta cell replication
Co-Investigator: Amy Cox, M.D.

 

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*These investigators have received funding from the Juvenile Diabetes Research Foundation (JDRF).