JDRF - Juvenile Diabetes Research Foundation International - Dedicated to finding a cure.

A quarterly e-newsletter for nPOD investigators, partners, and friends of the project. View the current nPOD newsletter.

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POD Scientific Investigators (updated June 25, 2010)
Category Investigator Institution Grant Title
Disease Etiology
Heikki Hyoty University of Tampere

Detection of viruses in pancreas and other tissues

  Ake Sjoholm

Karolinska Institutet

Ljungan virus in type 1 diabetes
  Gerald Taborsky University of Washington Sympathetic neuropathy in type 1 diabetes
  John Todd, Vincent Plagnol & Herbert Virgin University of Cambridge Viral sequence discovery by high throughput DNA
  Steve Tracy University of Nebraska Enteroviral infection and type 1 diabetes
 
Eric Triplett and Martha Campbell-Thompson
University of Florida Gut microbiota in early type 1 diabetes
Immunology Manuela Battaglia and Ezio Bonifacio San Raffaele Scientific Institute Dissecting the effector/regulatory compartments in the target tissues of type 1 diabetes
  Howard Davidson University of Colorado Autoantigen-specific PLN T-Cell receptors
  Garry Fathman Stanford University Microarray analysis of PLN from autoantibody positive donors
  Dale Greiner
University of Massachusetts
Diabetogenic function of nPOD donor splenocytes in humanized mice
  Sally Kent Harvard University Investigation of ß cells in human islets and PLN in type 1 diabetes
  Jerry Nadler Eastern Virginia Medical School 12/15 Lipoxygenase expression in type 1 diabetes
  Maki Nakayama and Joe Larkin, III University of Colorado and University of Florida TCR utilization in type 1 diabetes insulitis
  Jerry Nepom Benaroya Research Institute at Virgina Mason TCR repertoire analysis in type 1 diabetes
  Alberto Pugliese University of Miami Beta cells and autoimmunity correlations
  Helena Reijonen
Benaroya Research Institute at Virginia Mason
TCR repertoire analysis in type 1 diabetes
  Suparna Sarkar and Dirk Homann University of Colorado Pancreatic expression of chemokinesin human type 1 diabetes
  Jo Spencer
King's College London School of Medicine
Phenotype, specificity, diversity and clonal spread of ß cells in type 1 diabetes
  Matthias von Herrath
University of California, San Diego
Tetramer staining of pre-diabetic pancreata MHC
  Garth Warnock
University of British Columbia
T cell costimulatory molecules in pancreata from IAPCD
  Clive Wasserfall and Mark Pescovitz University of Florida Humoral immunity in type 1 diabetes
Islet and Pancreas Pathology
Martha Campbell Thompson and Mark Atkinson
University of Florida
Pancreatic immunologic and metabolic parameters
  Roberto Gianani and Mark Atkinson
University of Colorado and University of Florida
Histopathology of type 1 diabetes
  Akihisa Imagawa Osaka University Histological Differences Between Japanese and Western type 1 diabetes
  George King and Susan Bonner-Weir Harvard University Joslin Medalist Study
  Rudolph Leibel and Nao Wakae Columbia University E-cadherin mediates developmental effects of the proliferation and the function of ß-cells in the islet of Langerhans
  Paolo Maddedu and Costanza Emanueli University of Bristol Microangiopathy in diabetic bone marrow
  Brad Marsh University of Queensland
3D characterization of islet dysfunction/destruction
  Sara Michie Stanford University Tissue-selective Chemokines and Adhesion Molecules in type 1 diabetes
  Al Powers Vanderbilt University Islet biology and vascularization
  Lydia Sorokin and Eva Korpos University of Muenster Peri-capsular basement membrane degredation during leukocyte penetration into the pancreatic islet during development of human T1D
Metabolic and Developmental Jake Kushner University of Pennsylvania Do de-granulated ß-cells persist in type 1 diabetes?
  Douglas Melton Harvard University Generation of tools to distinguish human pancreatic cell populations
  Christopher Rhodes University of Chicago "Empty Beta Cells" in type 1 diabetes
New JDRF Funded Investigators Mark Stuart Anderson University of California, San Francisco Identification of extrathymic Aire-expressing cells in human lymph nodes
  Ivan Gerling University of Tennessee, Memphis Sequencing the islet transcriptome
  Dolores Jaraquemada Universitat Autonoma de Barcelona Tracing effector and regulatory T-cell populations in type 1 diabetes
  Richard David Leslie University of London Risk of autoimmune diseases in human self-antigen expression
  Clayton Mathews University of Florida Islet resistance to T1D
  Bart Roep Leiden University Detection of islet autoreactive CD8 T-cells in insulitis versus periphery
  Charmaine Simeonovic Australian National University Heparan sulfate levels mark the health status of human islet ß cells
  Ranjeny Thomas University of Queensland Pathological changes associated with chronic Re1B activation in T1D
  Thomas Wight Benaroya Institute at Virginia Mason Extracellular matrix involvement in type 1 diabetes pancreatic destruction