nPOD-Europe

What is nPOD-E?

The main goals of the nPOD-E project are to expand organ collection (and distribution) by creating a network for organ recovery at qualified sites in European countries, to provide these resources to all nPOD investigators and to provide nPOD European investigators with fresh tissue. nPOD will work in close collaboration with multiple sites in Europe modeled after nPOD.

Why is nPOD-E important?

Whereas many type 1 diabetes (T1D) research studies focus on one avenue of study to determine the cause of T1D, nPOD uses a multi-disciplinary approach and supports over 90 research projects worldwide, studying multiple pathways to understand the disease.

nPOD-E serves a very important role as the ‘bridge’ between the United States and Europe by establishing an exchange of tissue and data between nPOD and its affiliate sites in Europe.

How does nPOD-E work?

nPOD-E Operational sites are those established by nPOD, which will screen for autoantibodies, recover tissue from AAb+ and T1D donors, store specimen and specimen data, and distribute tissue to nPOD investigators, all utilizing the nPOD operational model:

  1. nPOD-E Spain works with Dr. Eduard Montanya at the University of Barcelona. This project screens and recovers AAb+ and T1D donors using nPOD SOPs for its screening, recovery, case processing and distribution methods. This project began in June, 2012.
  2. nPOD-E Italy collaborates with Dr. Francesco Dotta, from University of Siena.  This project screens and recovers AAb+ and T1D donors from several areas of Italy, and uses all of nPOD’s SOPs for its screening, recovery, case processing and distribution methods. This project began in June, 2012.
  3. nPOD-E Sardinia under the direction of Dr. Marco Songini at L’Azienda Ospedaliera Brotzu. This project screens and recovers AAb+ and T1D donors from the island of Sardinia, noted for its high T1D rate. Expected start date is Summer 2013.
  4. nPOD-E Finland is a project that will be set up like those already established in Spain & Italy. This project will be hosted at the University of Tampere, under the direction of Dr. Heikki Hyöty. Expected start date is October 2013.

Continued European Collaboration. Now that nPOD has an established presence in Europe, we will be able to maintain healthy collaborative relationships with other T1D research projects in Europe. For example, the PEVNET (PI: Dr. Hyöty in Finland) is a major, multicenter organ recovery initiative in Europe. PEVNET has included nPOD as a collaborator since its inception.

Please contact Jayne Moraski, nPOD Assistant Director, for further information.