For Investigators. 2012 nPOD Annual Meeting Presentations for Distribution

In order to view any of ther presentations below, you must be an approved nPOD investigator and you will need to input the username and password distributed to you for the purpose of viewing investigator documents.

Session 1: Viral Etiology

Title: Replication Defective Enterovirus Infections: Implications for Type 1 Diabetes
Presenter: Nora Chapman

Title: Detection of Enteroviruses in Tissue Samples of Cadaveric Organ Donors with Type 1 Diabetes
Presenter: Heikki Hyöty

Title: Detection of Enteroviral Proteins and Cellular Antiviral Responses in the Islets of Type 1 Diabetes Patients: A Comparative Analysis of Two Cohorts
Presenter: Sarah Richardson

Title: nPOD Viral Workgroup Introduction/Overview
Presenter: Alberto Pugliese

Title: nPOD Viral Workgroup – Update of Collaborative Plans and Ongoing Activities for IHC Studies
Presenter: Sarah Richardson

Title: nPOD Case 6052 – Focal MHC Class I Hyperexpression and Insulitis
Presenter: Ken Coppieters

Session 2: Autoantigens, T Cells and TCRs: Human Disease-specific Therapeutic Targets

Title: Defining Primary Trimolecular Complex for Type 1 Diabetes Mellitus
Presenter: George Eisenbarth

Title: In-situ Detection of Islet Antigen-specific CD8 T Cells in Insulitic Lesions of New-onset and Long-term Type 1 Diabetes Patients
Presenter: Ken Coppieters

Title: 454 Pyro-sequencing of T Cell Receptors Targeting Pancreatic Islets
Presenter: Maki Nakayama

Title: Monoclonal Expansions of TCR in a Diabetic Pancreas
Presenter: Mercè Martí

Session 3: Heterogeneity of Pancreas Pathology and Disease Mechanisms

Title: Expression and Regulation of Chemokines in Human Islets and Type 1 Diabetes
Presenter: Suparna Sarkar

Title: Down Regulation of Glucokinase and Mitochodrial ATP Synthase from Type 1 Organ Donors
Presenter: Yaíma Lightfoot

Title: Complement Activation in Type 1 Diabetes: Analysis of Pancreatic Tissue from nPOD Cases
Presenter: Patrick Rowe

Title: Adhesion Molecules on High Endothelial Venules of Pancreatic Lymph Nodes from Humans with Type 1 Diabetes
Presenter: Sara Michie

Session 4: From Genetics to Gene Expression in nPOD Tissues

Title: Regulation of Self-antigen Expression in Relation to Self-tolerance
Presenter: Alberto Pugliese

Title: Disease-dependent and Tissue-specific Changes in Gene Expression in Type 1 Diabetes
Presenter: Garry Fathman

Title: Identification of Extra-thymic Aire-expressing Cells (eTACs) in Human Tissue and Comparison between Type 1 Diabetic and Non-diabetic Controls
Presenter: Eileen McMahon

Session 5: What’s New at nPOD?

Title: What’s New at nPOD
Presenters: Martha Campbell-Thompson, Desmond Schatz, Clive Wasserfall, Jayne Moraski, Suzy Ball, Amy Wright, John Kaddis, Mark Atkinson, Carmen Retrum, Alberto Pugliese

Session 6: Emerging Technologies and Novel Research Avenues

Title: The Bone Marrow in Type 1 Diabetes – Feasibility of Flow Cytometric Analysis of nPOD Bone Marrow Specimens
Presenter: Paolo Madeddu

Title: The Role of IA-2 Extracellular Domain in Type 1 Diabetes Progression
Presenter: Michael Morran

Title: In Vitro Evaluation of Non-specific Binding of the Candidate Beta Cell Mass PET Probe (+) 18F-FP-DTBZ
Presenter: Paul Harris

Session 7: Pancreas and Beta Cell Biology

Title: The Pancreatic Duct Gland Compartment in Non-diabetic and Type 1 Diabetic Subjects
Presenter: Peter Butler

Title: Formation of a Baseline Pancreatic Beta Cell Mass in Humans is Completed Early in Life
Presenter: Chris Rhodes

Title: Beta Cells Persist in Some T1DM Pancreata without Attempted Evidence of Beta Cell Turnover nor Insulin-Glucagon Co-expression
Presenter: Dan Jacobson

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